eCM (Eur Cell Mater / e Cells & Materials)
eCM Conferences, Science with Open Discussion
 ISSN 2522-235X

Biotechnology Symposium
From basic research to clinical applications using biotechnology and bioengineering. Lausanne, Switzerland, October 19 to 21, 2006

Seminar organized by
AO Biotechnology Advisory Board
with the support of
AO Research Board
AO Research Fund
in collaboration with
the SMPA University Hospital Lausanne, CHUV, Lausanne, Switzerland


The use of biotechnology has become increasingly important in improving existing therapies and the quality of patient care. Both biomaterial and material technologies have been successfully applied in trauma and orthopedic surgery for many years including the use of metal alloys based on titanium and iron, natural and synthetic polymers, and inorganic materials like hydroxyapatite and beta-tricalcium phosphate. The use of nonmetallic natural and synthetic materials have formed the basis of tissue engineering. Substantial research work has focused on the controlled delivery of cells and a variety of bioactive molecules, and combinations of synthetic materials to stimulate new bone formation and fracture healing. The future of biotechnology in trauma and orthopedic research will involve a combination of tissue engineering, gene manipulation, cellbased therapies, and complex new drugs with sophisticated modes of targeting and delivery.
These trends are already emerging. Many technical, surgical, and ethical problems must be addressed while biotechnology is evolving to meet these clinical needs. Differences in outcome between results in animal models and those in humans must also be addressed.
The demands for such research and specific answers to clinical problems are increasing.

This meeting provided an overview of the state-of-the-art in biotechnology research funded by the AO Foundation. It was designed to promote networking within the community of researchers and clinicians active in this field, improve knowledge transfer, and exchange and stimulate new creative collaborations in R&D in this field.

The Organizers


• Margarethe Hofmann-Amtenbrink, Mat Search, Pully, CH, Chairwoman
• Stephen E Feinberg, University of Michigan, Ann Arbor, USA
• David W Grainger, University of Utah, USA
• Norbert Haas, Universitätsklinikum Charité, Berlin, DE
• Dick Heinegard, Department of Experimental Medical Science, Lund, SE
• David M Nunamaker, University of Pennsylvania, USA
• Robin Poole, McGill University, Montreal, CAN
• Jocelyn Urban, Dept. of Physiology, Anatomy and Genetics, Oxford University, UK
• Elliott Gruskin, Synthes (USA), West Chester, USA


• Norbert Suedkamp, Universitätsklinikum der Albert-Ludwigs-Universität, Freiburg, DE


• Adrian Sugar, Morriston Hospital, Wales, UK

View the abstracts